October 2006
China Experiencing Rapid Growth of Biotech Industry
With approximately 200 dedicated biotechnology research centers and more than 500 private biotech companies, China has become an international competitor in the biotech market. The country is active in developing and manufacturing biopharmaceuticals , biotech-based agrochemicals, and industrial biotechnology products.

Over 20 recombinant pharmaceutical actives have been commercialized in the country, with expertise in gene therapy and antibodies predominant. Generic production accounts for the majority of biotech activity, though. In 2002, eight out of 10 leading biopharmaceuticals were manufactured in China. With many more biotech based drugs coming off-patent in the next several years, the lower cost position of Chinese producers is very attractive.

Agricultural applications of biotechnology are of significant interest in China, with the government alone investing about $500 million per year. The country is the fourth largest grower of genetically modified crops. Researchers are exploring tissue culture, genetic engineering, marker-assisted selection, microbiology, genomics, and other techniques to develop plant species and functional genes. Crops receiving attention include cotton, rice, potato, soya bean, cucumber, papaya, maize and tobacco.

Industrial biotechnology in China has focused on bioethanol production. The government has launched a national bioethanol program and hopes to achieve 10 percent blending of biofuels. Significant increases in capacity will be required to meet rapidly growing domestic consumption levels. The Chinese government has also invested in the development of biodegradable, biotech based plastics such as Polylactic acid (PLA) and polyhydroxyalkanoates (PHA). Bioremediation and biocatalysis are other aspects of white biotechnology under investigation in China.
 

 

Famous Quotes of the Month
- The mistakes are all waiting to be made. (Savielly Grigorievitch Tartakower)
- Reality is merely an illusion, albeit a very persistent one. (Albert Einstein)
- One of the symptoms of an approaching nervous breakdown is the belief that one's work is terribly important. (Bertrand Russell)
- The possibilities are numerous once we decide to act and not react. (Gloria Anzaldua)
- Experience is the name everyone gives to their mistakes. (Oscar Wilde)
 

 



 

 
Why Do People Get Sick More Often In Winter?
There are many hypotheses for this but unfortunately there isn't any perfect answer. A leading theory is that confinement breeds infection. In winter, we spend more time indoors in rooms that may not get a lot of circulation. This gives us more opportunities to be exposed to respiratory viruses. The winter air, inside and outside, also tends to be less humid. This dries nasal passages and makes them more vulnerable to viral invasion. So while your mother told you not go out in the wintertime without wearing a jacket, the cold environment itself has not been proven to make people get sick in the winter.

 



 

 
Proposed Export Controls Could Hamper U.S. Chemicals Trade
Proposed rules from the U.S. Department of Commerce would broaden the definition of dual-use products, commodities and technology, or materials that have a legitimate commercial purpose but could potentially be used by the military of a receiving country. The rule specifically applies to goods exported to China and would cover much wider categories of materials. In general, exporters will have to certify to the Commerce Department's satisfaction that the end user in China is not part of the Chinese military or working with or to the benefit of the military. Exporters are concerned about the length of time it takes to receive certification or validation. They are also worried that Chinese traders will select other suppliers in order to avoid the issue, and fear that third party specifiers will choose non-US suppliers for the same reason. Overall they expect the rule to put them at great disadvantage to suppliers in Asia, Europe, and Israel.

 



 

 
Syngenta Reorganizes

In a move that is expected to save the company $40 million per year, Syngenta will reduce its workforce by 480 positions. Its crop protection development business in Manchester, U.K. will be closed by 2008 and will account for 330 jobs. Other positions will be eliminated at field stations located around the world and at additional sites in the UK, Switzerland, and the US.

 



 

 
Synthetech Appoints New Leader
Dr. Gregory Hahn became president and COO of Synthetech effective September 11, 2006. He succeeded M. "Sreeni" Sreenivasan, who will remain as CEO until his planned retirement on October 31, 2006. At that time, Synthetech's chairman of the board of directors, Dr. Daniel T. Fagan, will take on this role. Hahn most recently served as Organics Global Business Director for FMC's Lithium Division. He has also worked for Sigma Aldrich Fine Chemicals and Koch Chemical Company.

 



 

 
Altana Exits Pharma Business
Altana announced that it will begin to provide "future strategic development" for its pharma and chemicals businesses by selling the pharmaceutical operations to Nycomed for $5.75 billion (Euro 4.5 billion).

 



 
Merck KGaA Contributes to Pharma Industry Consolidation with Serono Purchase

The $13.3 billion (Euro 10.5 billion) acquisition of Serono will expand Merck KGaA's ethical drug sales and propel it to a leading position in biopharmaceuticals. This deal follows the company's failed attempt to purchase Schering, which was acquired by Bayer. The new entity (possibly Merck-Serono Biopharmaceuticals) would have 28 compounds in development and have strong expertise in neurology and oncology.

 



 
Mylan Plans Acquisition
Generic firm Mylan Laboratories announced that it plans to acquire a 71.5 percent stake in Indian API and final dosage form producer Matrix Laboratories for $736 million. The purchase will provide Mylan with access to the emerging markets of India, China and Africa as well as the large European market. Matrix in turn gains access to the U.S. market and expanded production capabilities.

 



 
UCB Announces Plans to Acquire Schwarz Pharma
The boards of both companies have agreed that, if regulatory approval is granted, UCB will acquire Schwarz Pharma for $5.6 billion (Euro 4.4 billion). The merged company will retain the name UCB. With the deal, UCB will gain access to several late stage drugs for diseases it targets as well as expand its position in the U.S. and Europe. The transaction is expected to close by the end of 2006.

 



 

 
BOC Takeover Completed
Linde finalized the $15.6 billion (GBP 8.2 billion, Euro 12.19 billion) acquisition of industrial gases firm BOC after receiving final approval from the U.K. court. Both the European Commission and the U.S. Federal Trade Commission awarded conditional approval to Linde earlier this summer, requiring the divestment of several different business units of Linde and BOC.

 



 
Uniqema Divestment to Croda Finalized

ICI announced the completion of its $781 million (GBP 410 million, Euro 609 million) sale of oleochemicals and surfactants business Uniqema to Croda International. ICI will use the proceeds to cover the costs of the deal and reduce post-retirement benefit deficits and net debt. For Croda, the acquisition improves the company's position in consumer care. The Uniqema specialty operations (esters, alkoxylates and performance additives) will be integrated into five different business groups, while the oleochemicals businesses of the two companies will be combined. Restructuring activities may include the disposal of some activities.

 



 

 
Growing Bioethanol Production Expected from New EU States
The European Commission expects the number of bioethanol plants in the ten new EU member countries to increase from 4 in 2005 to 20 in 2008. Plants in Hungary and Poland produced 135,000 tonne of bioethanol in 2005, a number that is predicted to grow to 1.12 million tonne by 2008. Biodiesel production is also expected to dramatically increase in Poland and the Czech Republic.

 



 

 
Benzene Flying High in U.S.
Tightness in supply led to record high October contract prices for Benzene in the U.S. Market players also believe that contract prices rose in response to the higher spot prices of the previous few weeks.

 



 
Bottom of the Barrel for Asian MTBE?
Asian Methyl tertiary butyl ether (MTBE) prices recently fell to a six month low and were anticipated to drop further. Prices have fallen nearly 30 percent since early April. Lower crude oil and gasoline values have impacted the MTBE market. In addition, falling prices in Europe have led some suppliers to ship material to Asia, leading to oversupply in the region and even lower MTBE prices.

 



 
High Time for European Propylene
Tight supplies and strong demand are driving spot prices for Propylene to record levels in Europe. Increasing demand for downstream products is occurring during a period of time when numerous crackers are shutdown for maintenance. U.S. producers are benefiting from the situation, which is expected to last at least through October.

 



 
Rising Ethylene Prices Boost Asian Petrochemical Profits
Spot prices for Asian Ethylene reached a 13 year high in September, while Naphtha prices remained low. Tightness in the market was exacerbated with the closure of over 20 percent of cracker capacity for maintenance. Downstream polymer prices, particularly for Polyethylene and Polypropylene, also peaked in September as seasonal demand rose while buyer inventories remained low. On the negative side, high crude oil prices have reduced margin gains for some suppliers. Integrated plants are expected to reap the biggest profits.

 



 
Spot Ethylene Prices Climbing in the U.S.
Unplanned outages in late August and September at U.S. crackers have resulted in rising spot prices for Ethylene in the country. The unexpected tightness in supply has stopped a slow downward trend in prices resulting from lower feedstock costs.

 



 
Tight Market Drives Cumene Prices
Rapidly growing global demand for Phenol has translated to higher prices for the feedstock Cumene in the U.S. Spot prices have risen nearly 10 percent. Most Cumene for Phenol manufacture is produced captively, but there usually is some material available on the spot market. Supplies are becoming increasingly difficult to find. The tightness in Cumene supply is expected to ease somewhat in September, however, when several European Phenol/Acetone plants will be shut down in for maintenance.

 



 
U.S. Soda Ash Market Strong
With producers operating at 98 percent capacity, tightness in the Soda ash market is expected to last through 2007. Annual supply contracts currently being negotiated include a price increase to reflect the short supply. Demand is strong in all markets (glass manufacturing, chemicals and soaps and detergents), with consumption for flat glass production the greatest.

 



 

 
Spot Prices for Butadiene Reach Peak
The tight supply and strong demand in the Butadiene market are expected to ease, causing a decline in the recent very high prices for this intermediate. As prices for natural rubber have declined, prices for Styrene Butadiene rubber (SBR) have also fallen. As a result, the peak prices for Butadiene, a key raw material for SBR, are expected to follow beginning in October.

 



 

 
EU Official Says Aggressive Approach Hurt Chemical Industry with Regard to Reach
According to Heinz Zourek, director general of the EU's Enterprise and Industry Directorate, the chemical industry took a much too aggressive approach when trying to influence the European Reach (registration, evaluation and authorization of chemicals) legislation. Chemical producers developed a poor public image, while downstream users of chemicals remained too quiet.

 



 
French Port Strike May Have Impacted the Chemical Industry
Shipments into and out of the port of Marseille were halted temporarily as the result of a 24 hour strike by port workers protesting plans to build a new terminal. Lavera and Fos, two areas within the port used for berthing chemical tankers, were affected by the strike. Arkema, Naphtachimie, Basell and Ineos have chemical operations near the port. No information was provided regarding whether any chemical shipments were delayed.

 



 

 
In This Issue

 
Famous Quotes
 
Imponderables
 
Business/Finance
 
Companies
 
Personnel
 
Pharma
 
Fine & Specialty Chemicals
 
Biotech
 
Commodity Chemicals
 
Intermediates
 
General
 
Featured Article
 

 






 

 

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